Lionel Messi was powerless to prevent Inter Miami from slipping to its biggest defeat in MLS play since his arrival in North America, falling 4-1 at Minnesota United on Saturday. Previously, there had only been one two-goal defeat with Messi — a 1-3 home loss to Atlanta United in May last year.

Miami played without forward Luis Suarez, who did not make the trip due to personal reasons, and without left winger Fafa Picault due to illness.

After getting things back on track with a victory over the New York Red Bulls, Lionel Messi and Inter Miami will begin a road trip that sees them face one of the best teams in the Western Conference, Minnesota United. The Loons have quietly risen to second in the conference behind a stout defense that will be pushed to the limits facing the Herons.