A study in mice has unpicked the neuronal circuitry responsible for pain suppression in threatening situations, pointing towards better pain relief treatments.

Self-supervised deep learning models can accurately perform 3D segmentation of cell nuclei in complex biological tissues, enabling scalable analysis in settings with limited or no ground truth ...

The attentional blink selectively impairs one component of attention, and impacts both target detection and discrimination via separable neural signatures.

The novel cue-induced analgesia paradigm allowed a compelling identification of a brainstem circuit element, i.e., somatostatin-expressing neurons within the ventrolateral periaqueductal grey that ...

This study introduces a valuable spring-bead model for epithelial cell layers, designed to improve previous cell-resolved approaches and to understand the connection between the biophysics of ...

Streptococcus suis ( S. suis) is an important zoonotic pathogen causing substantial economic losses in the swine industry. S. suis serotype 2 (SS2) is often isolated from the diseased. S. suis ...

Exosomal mRNA transfer from non-neuronal cells to neurons under hypoxia drives hemoglobin expression and preserves mitochondrial homeostasis as an intercellular protective mechanism.

Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...

Trained immunity is a form of innate immune cell memory that is being developed as a novel immunotherapeutic approach for cancer treatment.

This manuscript provides valuable information on the neurodynamics of emotional processing while participants were watching movie clips. The methods and results were solid in deciphering the ...

Rodent medial prefrontal cortex is not crucial for an active place avoidance task requiring cognitive control evidenced by hippocampal activity that purposefully alternates between task-relevant and ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...